In the field of medical imaging, a IRFU team has launched a challenge: their goal is to image the brain activity with a precision of 1 mm3. Its name: CaLIPSO. The idea consists in an innovative detector technology: both light and ionisation signals produced by particle interactions are detected. For this, a series of technological obstacles must be overcome. One of these crucial steps has just succeeded. It consists in implementing the entire chain of ultra-purification of the detection liquid.